LPL Antibody

Product Specifications

Background

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq].

NCBI Gene ID

4023

Swiss Prot

P06858

Accession Number

P06858

Host

Rabbit

Reactivity

Human

Immunogen

This LPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-327 amino acids from the Central region of human LPL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Symbol

LPL

NCBI Official Name

Lipoprotein lipase

NCBI Organism

Homo sapiens

Background Reference 01

Hu, M., et al. Pharmacogenet. Genomics 20 (10) :634-637 (2010)

Background Reference 02

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :

Background Reference 03

Johansen, C.T., et al. Nat. Genet. 42 (8) :684-687 (2010)

Background Reference 04

Zabaneh, D., et al. PLoS ONE (8) (2010) :

Other Product Names

Lipoprotein lipase, LPL, LPL, LIPD

Tested Applications

WB, IHC-P, Flow

Protein ID

126314

Physical Properties

Liquid

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