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UBP46 Antibody

Product Specifications

Background

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]) .

NCBI Gene ID

64854

Swiss Prot

P62068

Accession Number

P62068

Host

Rabbit

Reactivity

Human

Immunogen

This UBP46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human UBP46.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-525

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

USP46

NCBI Official Name

Ubiquitin carboxyl-terminal hydrolase 46

NCBI Organism

Homo sapiens

Background Reference 01

Kushima, I., et al. J. Hum. Genet. 55 (3) :133-136 (2010)

Background Reference 02

Cohn, M.A., et al. J. Biol. Chem. 284 (8) :5343-5351 (2009)

Background Reference 03

Zemunik, T., et al. Croat. Med. J. 50 (1) :23-33 (2009)

Background Reference 04

Quesada, V., et al. Biochem. Biophys. Res. Commun. 314 (1) :54-62 (2004)

Other Product Names

Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46, USP46

Tested Applications

WB

Protein ID

49065850

Physical Properties

Liquid

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