Mouse Map3k14 Antibody

Product Specifications

Background

Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.

NCBI Gene ID

53859

Swiss Prot

Q9WUL6

Accession Number

Q9WUL6

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 652-680 amino acids from the C-terminal region of mouse Map3k14.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

103 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Map3k14

NCBI Official Name

Mitogen-activated protein kinase kinase kinase 14

NCBI Organism

Mus musculus

Background Reference 01

Bhattacharyya, S., et al. Exp. Cell Res. 316 (19) :3317-3327 (2010)

Background Reference 02

Maeda, Y., et al. Int. Immunol. 22 (6) :515-525 (2010)

Background Reference 03

Sanjo, H., et al. J. Biol. Chem. 285 (22) :17148-17155 (2010)

Background Reference 04

Takeshima, T., et al. Cancer Res. 70 (7) :2697-2706 (2010)

Other Product Names

Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, Map3k14, Nik

Tested Applications

Physical Properties

Liquid

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