Mouse Ltk Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Four alternatively spliced transcript variants encoding different isoforms have been described for this gene. These transcripts are expressed in a tissue-specific manner in lymphocytes, brain and neuroblastoma cells, and the encoded isoforms exhibit different subcellular localization. The lymphocyte and brain specific variants initiate translation at non-AUG (CUG) start codons.
NCBI Gene ID
17005
Swiss Prot
P08923
Accession Number
P08923
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Ltk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 795-822 amino acids from the C-terminal region of mouse Ltk.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
94 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Ltk
NCBI Official Name
Leukocyte tyrosine kinase receptor
NCBI Organism
Mus musculus
Background Reference 01
Li, J., et al. J. Biol. Chem. 283 (49) :34260-34272 (2008)
Background Reference 02
Yu, X., et al. J. Immunol. 177 (10) :7042-7049 (2006)
Background Reference 03
Li, N., et al. Hum. Mol. Genet. 13 (2) :171-179 (2004)
Background Reference 04
Thut, C.J., et al. Dev. Biol. 231 (1) :63-76 (2001)
Other Product Names
Leukocyte tyrosine kinase receptor, Ltk
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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