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Mouse Ksr1 Antibody

Product Specifications

Background

Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.

NCBI Gene ID

16706

Swiss Prot

Q61097

Accession Number

Q61097

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Ksr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of mouse Ksr1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-513

Calculated Molecular Weight

97 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Ksr1

NCBI Official Name

Kinase suppressor of Ras 1

NCBI Organism

Mus musculus

Background Reference 01

Costanzo-Garvey, D.L., et al. Cell Metab. 10 (5) :366-378 (2009)

Background Reference 02

McKay, M.M., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (27) :11022-11027 (2009)

Background Reference 03

Razidlo, G.L., et al. J. Biol. Chem. 284 (11) :6705-6715 (2009)

Background Reference 04

Giurisato, E., et al. Mol. Cell. Biol. 29 (6) :1554-1564 (2009)

Other Product Names

Kinase suppressor of Ras 1, mKSR1, Protein Hb, Ksr1, Ksr

Tested Applications

WB

Physical Properties

Liquid

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