Mouse Irak4 Antibody

Product Specifications

Background

Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity) .

NCBI Gene ID

266632

Swiss Prot

Q8R4K2

Accession Number

Q8R4K2

Host

Rabbit

Reactivity

Human

Immunogen

This Mouse Irak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-449 amino acids from the C-terminal region of mouse Irak4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Irak4

NCBI Official Name

Interleukin-1 receptor-associated kinase 4

NCBI Organism

Mus musculus

Background Reference 01

Erdman, L.K., et al. J. Immunol. 183 (10) :6452-6459 (2009)

Background Reference 02

Maekawa, Y., et al. Circulation 120 (14) :1401-1414 (2009)

Background Reference 03

Bauernfeind, F.G., et al. J. Immunol. 183 (2) :787-791 (2009)

Background Reference 04

Staschke, K.A., et al. J. Immunol. 183 (1) :568-577 (2009)

Other Product Names

Interleukin-1 receptor-associated kinase 4, IRAK-4, Irak4

Tested Applications

Physical Properties

Liquid

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