HIC1 Antibody

Product Specifications

Background

This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants.

NCBI Gene ID

3090

Swiss Prot

Q14526

Accession Number

Q14526

Host

Rabbit

Reactivity

Human

Immunogen

This HIC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-527 amino acids from the C-terminal region of human HIC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

77 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HIC1

NCBI Official Name

Hypermethylated in cancer 1 protein

NCBI Organism

Homo sapiens

Background Reference 01

Pehlivan, S., et al. Cancer Genet. Cytogenet. 201 (2) :128-132 (2010)

Background Reference 02

Van Rechem, C., et al. Mol. Cell. Biol. 30 (16) :4045-4059 (2010)

Background Reference 03

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 04

Zhang, B., et al. Mol. Endocrinol. 23 (12) :2075-2085 (2009)

Other Product Names

Hypermethylated in cancer 1 protein, Hic-1, Zinc finger and BTB domain-containing protein 29, HIC1, ZBTB29

Tested Applications

Protein ID

296439502

Physical Properties

Liquid

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