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GTF2E2 Antibody

Product Specifications

Background

GTF2E2 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

NCBI Gene ID

2961

Swiss Prot

P29084

Accession Number

P29084

Host

Rabbit

Reactivity

Human

Immunogen

This GTF2E2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the C-terminal region of human GTF2E2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GTF2E2

NCBI Official Name

Transcription initiation factor IIE subunit beta

NCBI Organism

Homo sapiens

Background Reference 01

Cirulli, E.T., et al. Eur. J. Hum. Genet. 18 (7) :815-820 (2010)

Background Reference 02

Festen, E.A., et al. Am. J. Gastroenterol. 105 (2) :395-402 (2010)

Background Reference 03

Tanaka, A., et al. Genes Cells 14 (3) :395-405 (2009)

Background Reference 04

Jawhari, A., et al. EMBO Rep. 7 (5) :500-505 (2006)

Other Product Names

Transcription initiation factor IIE subunit beta, TFIIE-beta, General transcription factor IIE subunit 2, GTF2E2, TF2E2

Tested Applications

WB

Protein ID

135232

Physical Properties

Liquid

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