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SOX9 Antibody

Product Specifications

Background

SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

NCBI Gene ID

6662

Swiss Prot

P48436

Accession Number

P48436

Host

Rabbit

Reactivity

Human

Immunogen

This SOX9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human SOX9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Symbol

SOX9

NCBI Official Name

Transcription factor SOX-9

NCBI Organism

Homo sapiens

Background Reference 01

Malki, S., Cancer Lett. 255 (2), 182-193 (2007)

Background Reference 02

Passeron, T., Proc. Natl. Acad. Sci. U.S.A. 104 (35), 13984-13989 (2007)

Other Product Names

Transcription factor SOX-9, SOX9

Tested Applications

WB, IHC-P, IF

Protein ID

1351096

Physical Properties

Liquid

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