FARSB Antibody

Product Specifications

Background

This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified.

NCBI Gene ID

10056

Swiss Prot

Q9NSD9

Accession Number

Q9NSD9

Host

Rabbit

Reactivity

Human

Immunogen

This FARSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-564 amino acids from the C-terminal region of human FARSB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

66 kDa

Fragment

Rabbit Ig

Symbol

FARSB

NCBI Official Name

Phenylalanine--tRNA ligase beta subunit

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Finarov, I., et al. Structure 18 (3) :343-353 (2010)

Background Reference 03

Yu, X.Y., et al. Bioorg. Med. Chem. Lett. 14 (5) :1339-1342 (2004)

Background Reference 04

Vasil'eva, I.A., et al. Biochemistry Mosc. 69 (2) :143-153 (2004)

Other Product Names

Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS, FARSB, FARSLB, FRSB

Tested Applications

WB, IHC-P

Protein ID

296452943

Physical Properties

Liquid

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