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Mouse Pkmyt1 Antibody

Product Specifications

Background

Pkmyt1 acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development (By similarity) .

NCBI Gene ID

268930

Swiss Prot

Q9ESG9

Accession Number

Q9ESG9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Pkmyt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of mouse Pkmyt1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Pkmyt1

NCBI Official Name

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

NCBI Organism

Mus musculus

Other Product Names

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, Myt1 kinase, Pkmyt1, Myt1

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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