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Mouse Pdk2 Antibody

Product Specifications

Background

Pdk2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

NCBI Gene ID

18604

Swiss Prot

Q9JK42

Accession Number

Q9JK42

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Pdk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-107 amino acids from the N-terminal region of mouse Pdk2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-463

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Symbol

Pdk2

NCBI Official Name

[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 2, mitochondrial

NCBI Organism

Mus musculus

Background Reference 01

Sun, W., et al. Clin. Cancer Res. 15 (2) :476-484 (2009)

Background Reference 02

Pagliarini, D.J., et al. Cell 134 (1) :112-123 (2008)

Background Reference 03

Osafune, K., et al. Development 133 (1) :151-161 (2006)

Background Reference 04

Papin, J., et al. Curr. Opin. Biotechnol. 15 (1) :78-81 (2004)

Other Product Names

[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 2, mitochondrial, Pyruvate dehydrogenase kinase isoform 2, PDH kinase 2, Pdk2

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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