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Mouse Npr1 Antibody

Product Specifications

Background

Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.

NCBI Gene ID

18160

Swiss Prot

P18293

Accession Number

P18293

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Npr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the N-terminal region of mouse Npr1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

119 kDa

Fragment

Rabbit Ig

Symbol

Npr1

NCBI Official Name

Atrial natriuretic peptide receptor 1

NCBI Organism

Mus musculus

Background Reference 01

Madhani, M., et al. Am. J. Physiol. Heart Circ. Physiol. 299 (3), H827-H836 (2010) :

Background Reference 02

Panayiotou, C.M., et al. Br. J. Pharmacol. 160 (8) :2045-2054 (2010)

Background Reference 03

Ropero, A.B., et al. Endocrinology 151 (8) :3665-3674 (2010)

Background Reference 04

Tankersley, C.G., et al. Inhal Toxicol 22 (8) :695-707 (2010)

Other Product Names

Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A, ANP-A, ANPR-A, NPR-A, Guanylate cyclase A, GC-A, Npr1, Npra

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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