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SYT5 Antibody

Product Specifications

Background

SYT5 may be involved in Ca (2+) -dependent exocytosis of secretory vesicles through Ca (2+) and phospholipid binding to the C2 domain or may serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca (2+) -dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity) .

NCBI Gene ID

6861

Swiss Prot

O00445

Accession Number

O00445

Host

Rabbit

Reactivity

Human

Immunogen

This SYT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the Central region of human SYT5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SYT5

NCBI Official Name

Synaptotagmin-5

NCBI Organism

Homo sapiens

Background Reference 01

Martins-de-Souza, D., et al.Psychiatr Res (2010) In press :

Background Reference 02

Sreenath, A.S., et al. Clin. Biochem. 38 (5) :436-443 (2005)

Background Reference 03

Mizutani, A., et al. J. Biol. Chem. 275 (13) :9823-9831 (2000)

Background Reference 04

Craxton, M., et al. FEBS Lett. 460 (3) :417-422 (1999)

Other Product Names

Synaptotagmin-5, Synaptotagmin V, SytV, SYT5

Tested Applications

WB

Physical Properties

Liquid

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