AVPR1B Antibody

Product Specifications

Background

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.

NCBI Gene ID

553

Swiss Prot

P47901

Accession Number

P47901

Host

Rabbit

Reactivity

Human

Immunogen

This AVPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the C-terminal region of human AVPR1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AVPR1B

NCBI Official Name

Vasopressin V1b receptor

NCBI Organism

Homo sapiens

Background Reference 01

Van West, D., et al. Psychiatry Res 179 (1) :64-68 (2010)

Background Reference 02

Binder, E.B., et al. Arch. Gen. Psychiatry 67 (4) :369-379 (2010)

Background Reference 03

Bosker, F.J., et al. Mol. Psychiatry (2010) In press :

Background Reference 04

Van West, D., et al. Psychiatr. Genet. 19 (2) :102-103 (2009)

Other Product Names

Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3

Tested Applications

Protein ID

1351392

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

HY-135775-01 5 mg

BMVC

Ask

View Details

HY-135775-02 10 mM - 1 mL

BMVC

Ask

View Details

HY-135775-03 10 mg

BMVC

Ask

View Details

HY-135775-04 25 mg

BMVC

Ask

View Details

HY-135775-05 50 mg

BMVC

Ask

View Details

HY-135775-06 100 mg

BMVC

Ask

View Details