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SNX1 Antibody

Product Specifications

Background

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.

NCBI Gene ID

6642

Swiss Prot

Q13596

Accession Number

Q13596

Host

Rabbit

Reactivity

Human

Immunogen

This SNX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human SNX1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-439

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SNX1

NCBI Official Name

Sorting nexin-1

NCBI Organism

Homo sapiens

Background Reference 01

Nisar, S., et al. Traffic 11 (4) :508-519 (2010)

Background Reference 02

Mari, M., et al. Traffic 9 (3) :380-393 (2008)

Background Reference 03

Bryant, D.M., et al. J. Cell. Sci. 120 (PT 10), 1818-1828 (2007) :

Background Reference 04

Rojas, R., et al. Mol. Cell. Biol. 27 (3) :1112-1124 (2007)

Other Product Names

Sorting nexin-1, SNX1

Tested Applications

WB

Protein ID

17380569

Physical Properties

Liquid

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