SNX1 Antibody
Product Specifications
Background
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
NCBI Gene ID
6642
Swiss Prot
Q13596
Accession Number
Q13596
Host
Rabbit
Reactivity
Human
Immunogen
This SNX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human SNX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SNX1
NCBI Official Name
Sorting nexin-1
NCBI Organism
Homo sapiens
Background Reference 01
Nisar, S., et al. Traffic 11 (4) :508-519 (2010)
Background Reference 02
Mari, M., et al. Traffic 9 (3) :380-393 (2008)
Background Reference 03
Bryant, D.M., et al. J. Cell. Sci. 120 (PT 10), 1818-1828 (2007) :
Background Reference 04
Rojas, R., et al. Mol. Cell. Biol. 27 (3) :1112-1124 (2007)
Other Product Names
Sorting nexin-1, SNX1
Tested Applications
WB
Protein ID
17380569
Physical Properties
Liquid
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