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GABPA Antibody

Product Specifications

Background

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

2551

Swiss Prot

Q06546

Accession Number

Q06546

Host

Rabbit

Reactivity

Human

Immunogen

This GABPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the Central region of human GABPA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-435

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GABPA

NCBI Official Name

GA-binding protein alpha chain

NCBI Organism

Homo sapiens

Background Reference 01

Henderson, A.J., et al. Thorax 65 (10) :897-902 (2010)

Background Reference 02

Eynon, N., et al. Physiol. Genomics 41 (1) :78-81 (2010)

Background Reference 03

Levy, S., et al. IUBMB Life 62 (3) :237-246 (2010)

Background Reference 04

Kim, Y.R., et al. J. Pathol. 220 (4) :446-451 (2010)

Other Product Names

GA-binding protein alpha chain, GABP subunit alpha, Nuclear respiratory factor 2 subunit alpha, Transcription factor E4TF1-60, GABPA, E4TF1A

Tested Applications

WB

Protein ID

729553

Physical Properties

Liquid

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