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HCLS1 Antibody

Product Specifications

Background

Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.

NCBI Gene ID

3059

Swiss Prot

P14317

Accession Number

P14317

Host

Rabbit

Reactivity

Human

Immunogen

This HCLS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 362-391 amino acids from the C-terminal region of human HCLS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

HCLS1

NCBI Official Name

Hematopoietic lineage cell-specific protein

NCBI Organism

Homo sapiens

Background Reference 01

Muzio, M., et al. Leukemia 21 (9) :2067-2070 (2007)

Background Reference 02

Lim, J., et al. Cell 125 (4) :801-814 (2006)

Background Reference 03

Hao, J.J., et al. J. Biol. Chem. 280 (45) :37988-37994 (2005)

Background Reference 04

Tao, W.A., et al. Nat. Methods 2 (8) :591-598 (2005)

Other Product Names

Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75, HCLS1, HS1

Tested Applications

WB, IHC-P

Protein ID

317373440

Physical Properties

Liquid

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