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CYB5A Antibody

Product Specifications

Background

The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

1528

Swiss Prot

P00167

Accession Number

P00167

Host

Rabbit

Reactivity

Human

Immunogen

This CYB5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the Central region of human CYB5A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-429

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Symbol

CYB5A

NCBI Official Name

Cytochrome b5

NCBI Organism

Homo sapiens

Background Reference 01

Gardner, A.M., et al. J. Biol. Chem. 285 (31) :23850-23857 (2010)

Background Reference 02

Kok, R.C., et al. J. Clin. Endocrinol. Metab. 95 (3) :994-999 (2010)

Background Reference 03

Sacco, J.C., et al. Pharmacogenet. Genomics 20 (1) :26-37 (2010)

Background Reference 04

Maghzal, G.J., et al. J. Biol. Chem. 283 (18) :12014-12025 (2008)

Other Product Names

Cytochrome b5, Microsomal cytochrome b5 type A, MCB5, CYB5A, CYB5

Tested Applications

WB, IHC-P

Protein ID

117809

Physical Properties

Liquid

Curated Selection

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