NPPC Antibody
Product Specifications
Background
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.
NCBI Gene ID
4880
Swiss Prot
P23582
Accession Number
P23582
Host
Rabbit
Reactivity
Human
Immunogen
This NPPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the C-terminal region of human NPPC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
13 kDa
Fragment
Rabbit Ig
Symbol
NPPC
NCBI Official Name
C-type natriuretic peptide
NCBI Organism
Homo sapiens
Background Reference 01
Lippert, S.K., et al. J. Immunol. Methods 362 (1-2), 32-37 (2010) :
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)
Background Reference 04
Wang, Y., et al. J. Cardiovasc. Pharmacol. 55 (1) :62-66 (2010)
Other Product Names
C-type natriuretic peptide, CNP-22, CNP-29, CNP-53, NPPC, CNP2
Tested Applications
WB, IHC-P
Protein ID
113850
Physical Properties
Liquid
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