ODC1 Antibody
Product Specifications
Background
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.
NCBI Gene ID
4953
Swiss Prot
P11926
Accession Number
P11926
Host
Rabbit
Reactivity
Human
Immunogen
This ODC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of human ODC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ODC1
NCBI Official Name
Ornithine decarboxylase
NCBI Organism
Homo sapiens
Background Reference 01
Chaturvedi, R., et al. Gastroenterology 139 (5) :1686-1698 (2010)
Background Reference 02
Zell, J.A., et al. J. Natl. Cancer Inst. 102 (19) :1513-1516 (2010)
Background Reference 03
Geerts, D., et al. Int. J. Cancer 126 (9) :2012-2024 (2010)
Background Reference 04
Hughes, D., et al. Colorectal Dis (2010) In press :
Other Product Names
Ornithine decarboxylase, ODC, ODC1
Tested Applications
WB
Protein ID
118377
Physical Properties
Liquid
Frequently Asked Questions
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