IL1R1 Antibody
Product Specifications
Background
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA) . It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
NCBI Gene ID
3554
Swiss Prot
P14778
Accession Number
P14778
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This IL1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human IL1R1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=57-404
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
IL1R1
NCBI Official Name
Interleukin-1 receptor type 1
NCBI Organism
Homo sapiens
Background Reference 01
Fragoso, J.M., et al. Immunol. Lett. 133 (2) :106-111 (2010)
Background Reference 02
Franchim, C.S., et al. Hypertens Pregnancy (2010) In press :
Background Reference 03
Melen, E., et al. J. Allergy Clin. Immunol. 126 (3) :631-637 (2010)
Background Reference 04
De Wit, E., et al. Mamm. Genome (2010) In press :
Other Product Names
Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a, Interleukin-1 receptor type 1, membrane form, mIL-1R1, mIL-1RI, Interleukin-1 receptor type 1, soluble form, sIL-1R1, sIL-1RI, IL1R1, IL1R, IL1RA, IL1RT1
Tested Applications
WB
Protein ID
124308
Physical Properties
Liquid
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