MYB Antibody
Product Specifications
Background
This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
4602
Swiss Prot
P10242
Accession Number
P10242
Host
Rabbit
Reactivity
Human
Immunogen
This MYB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the Central region of human MYB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
Rabbit Ig
Symbol
MYB
NCBI Official Name
Transcriptional activator Myb
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Tanno, B., et al. J. Biol. Chem. 285 (38) :29434-29445 (2010)
Background Reference 03
Melen, E., et al. J. Allergy Clin. Immunol. 126 (3) :631-637 (2010)
Background Reference 04
Stenman, G., et al. Cell Cycle 9 (15) :2986-2995 (2010)
Other Product Names
Transcriptional activator Myb, Proto-oncogene c-Myb, MYB
Tested Applications
WB, IHC-P
Protein ID
2815504
Physical Properties
Liquid
Frequently Asked Questions
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