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PPCDC Antibody

Product Specifications

Background

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]) .

NCBI Gene ID

60490

Swiss Prot

Q96CD2

Accession Number

Q96CD2

Host

Rabbit

Reactivity

Mouse

Immunogen

This PPCDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PPCDC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPCDC

NCBI Official Name

Phosphopantothenoylcysteine decarboxylase

NCBI Organism

Homo sapiens

Background Reference 01

Strauss, E., et al. Biochemistry 43 (49) :15520-15533 (2004)

Background Reference 02

Manoj, N., et al. Acta Crystallogr.Biol. Crystallogr. 59 (PT 10), 1762-1766 (2003) :

Background Reference 03

Daugherty, M., et al. J. Biol. Chem. 277 (24) :21431-21439 (2002)

Other Product Names

Phosphopantothenoylcysteine decarboxylase, PPC-DC, CoaC, PPCDC, COAC

Tested Applications

WB

Protein ID

296434457

Physical Properties

Liquid

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