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ERG25 Antibody

Product Specifications

Background

Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

NCBI Gene ID

6307

Swiss Prot

Q15800

Accession Number

Q15800

Host

Rabbit

Reactivity

Human

Immunogen

This ERG25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-293 amino acids from the C-terminal region of human ERG25.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-377

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

MSMO1

NCBI Official Name

Methylsterol monooxygenase 1

NCBI Organism

Homo sapiens

Background Reference 01

Lu, Y., et al. J. Lipid Res. 49 (12) :2582-2589 (2008)

Background Reference 02

Lim, J., et al. Cell 125 (4) :801-814 (2006)

Background Reference 03

Li, L., et al. J. Biol. Chem. 271 (28) :16927-16933 (1996)

Other Product Names

Methylsterol monooxygenase 1, C-4 methylsterol oxidase, MSMO1, DESP4, ERG25, SC4MOL

Tested Applications

WB, IHC-P

Protein ID

2498340

Physical Properties

Liquid

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