WNT8B Antibody
Product Specifications
Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.
NCBI Gene ID
7479
Swiss Prot
Q93098
Accession Number
Q93098
Host
Rabbit
Reactivity
Human
Immunogen
This WNT8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human WNT8B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
WNT8B
NCBI Official Name
Protein Wnt-8b
NCBI Organism
Homo sapiens
Background Reference 01
Katoh, M., et al. Int. J. Oncol. 30 (5) :1273-1277 (2007)
Background Reference 02
Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)
Background Reference 03
Deloukas, P., et al. Nature 429 (6990) :375-381 (2004)
Background Reference 04
Saitoh, T., et al. Int. J. Oncol. 20 (5) :999-1003 (2002)
Other Product Names
Protein Wnt-8b, WNT8B
Tested Applications
WB
Protein ID
66774217
Physical Properties
Liquid
Curated Selection
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