SLC22A1 Antibody
Product Specifications
Background
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq].
NCBI Gene ID
6580
Swiss Prot
O15245
Accession Number
O15245
Host
Rabbit
Reactivity
Human
Immunogen
This SLC22A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the C-terminal region of human SLC22A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Symbol
SLC22A1
NCBI Official Name
Solute carrier family 22 member 1
NCBI Organism
Homo sapiens
Background Reference 01
Takahashi, N., et al. J. Hum. Genet. 55 (11) :731-737 (2010)
Background Reference 02
Jablonski, K.A., et al. Diabetes 59 (10) :2672-2681 (2010)
Background Reference 03
Hu, M., et al. Pharmacogenet. Genomics 20 (10) :634-637 (2010)
Background Reference 04
Gambineri, A., et al. J. Clin. Endocrinol. Metab. 95 (10), E204-E208 (2010) :
Other Product Names
Solute carrier family 22 member 1, Organic cation transporter 1, hOCT1, SLC22A1, OCT1
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Frequently Asked Questions
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