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SLC22A1 Antibody

Product Specifications

Background

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq].

NCBI Gene ID

6580

Swiss Prot

O15245

Accession Number

O15245

Host

Rabbit

Reactivity

Human

Immunogen

This SLC22A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the C-terminal region of human SLC22A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-369

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Symbol

SLC22A1

NCBI Official Name

Solute carrier family 22 member 1

NCBI Organism

Homo sapiens

Background Reference 01

Takahashi, N., et al. J. Hum. Genet. 55 (11) :731-737 (2010)

Background Reference 02

Jablonski, K.A., et al. Diabetes 59 (10) :2672-2681 (2010)

Background Reference 03

Hu, M., et al. Pharmacogenet. Genomics 20 (10) :634-637 (2010)

Background Reference 04

Gambineri, A., et al. J. Clin. Endocrinol. Metab. 95 (10), E204-E208 (2010) :

Other Product Names

Solute carrier family 22 member 1, Organic cation transporter 1, hOCT1, SLC22A1, OCT1

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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