ABP1 Antibody

Product Specifications

Background

This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

NCBI Gene ID

Swiss Prot

P19801

Accession Number

P19801

Host

Rabbit

Reactivity

Human

Immunogen

This ABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human ABP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

85 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AOC1

NCBI Official Name

Amiloride-sensitive amine oxidase [copper-containing]

NCBI Organism

Homo sapiens

Background Reference 01

Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)

Background Reference 02

McGrath, A.P., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 66 (PT 2), 137-142 (2010) :

Background Reference 03

Chambers, J.C., et al. Nat. Genet. 42 (2) :149-152 (2010)

Background Reference 04

McGrath, A.P., et al. Biochemistry 48 (41) :9810-9822 (2009)

Other Product Names

Amiloride-sensitive amine oxidase [copper-containing], DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, AOC1, ABP1, DAO1