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Mouse Ntrk2 Antibody

Product Specifications

Background

Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF) . Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

NCBI Gene ID

18212

Swiss Prot

P15209

Accession Number

P15209

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Ntrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the Central region of mouse Ntrk2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-360

Calculated Molecular Weight

92 kDa

Fragment

Rabbit Ig

Symbol

Ntrk2

NCBI Official Name

BDNF/NT-3 growth factors receptor

NCBI Organism

Mus musculus

Background Reference 01

Xu, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (44) :19126-19131 (2010)

Background Reference 02

Lobo, M.K., et al. Science 330 (6002) :385-390 (2010)

Background Reference 03

Gascon, E., et al. J. Neurosci. 30 (37) :12414-12423 (2010)

Background Reference 04

Nikoletopoulou, V., et al. Nature 467 (7311) :59-63 (2010)

Other Product Names

BDNF/NT-3 growth factors receptor, GP145-TrkB/GP95-TrkB, Trk-B, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Ntrk2, Trkb

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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