Mouse Mknk2 Antibody

Product Specifications

Background

Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity) .

NCBI Gene ID

17347

Swiss Prot

Q8CDB0

Accession Number

Q8CDB0

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Mknk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of mouse Mknk2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Mknk2

NCBI Official Name

MAP kinase-interacting serine/threonine-protein kinase 2

NCBI Organism

Mus musculus

Background Reference 01

Ueda, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (32) :13984-13990 (2010)

Background Reference 02

Furic, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (32) :14134-14139 (2010)

Background Reference 03

Joshi, S., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (29) :12097-12102 (2009)

Background Reference 04

Chrestensen, C.A., et al. Genes Cells 12 (10) :1133-1140 (2007)

Other Product Names

MAP kinase-interacting serine/threonine-protein kinase 2, MAP kinase signal-integrating kinase 2, MAPK signal-integrating kinase 2, Mnk2, Mknk2, Mnk2

Tested Applications

Physical Properties

Liquid

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