AP2A1 Antibody
Product Specifications
Background
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma) . The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.
NCBI Gene ID
160
Swiss Prot
O95782
Accession Number
O95782
Host
Rabbit
Reactivity
Human
Immunogen
This AP2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-735 amino acids from the C-terminal region of human AP2A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=57-344
Calculated Molecular Weight
108 kDa
Fragment
Rabbit Ig
Symbol
AP2A1
NCBI Official Name
AP-2 complex subunit alpha-1
NCBI Organism
Homo sapiens
Background Reference 01
Mitchell, R.S., et al. J. Virol. 82 (16) :7758-7767 (2008)
Background Reference 02
Kitagawa, Y., et al. Virology 373 (1) :171-180 (2008)
Background Reference 03
Stove, V., et al. J. Virol. 79 (17) :11422-11433 (2005)
Background Reference 04
Lu, W., et al. Neuron 47 (3) :407-421 (2005)
Other Product Names
AP-2 complex subunit alpha-1, 100 kDa coated vesicle protein A, Adaptor protein complex AP-2 subunit alpha-1, Adaptor-related protein complex 2 subunit alpha-1, Alpha-adaptin A, Alpha1-adaptin, Clathrin assembly protein complex 2 alpha-A large chain, Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit, AP2A1, ADTAA, CLAPA1
Tested Applications
WB, IHC-P
Physical Properties
Liquid
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