CUL4A Antibody
Product Specifications
Background
CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]) .
NCBI Gene ID
8451
Swiss Prot
Q13619
Accession Number
Q13619
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CUL4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human CUL4A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CUL4A
NCBI Official Name
Cullin-4A
NCBI Organism
Homo sapiens
Background Reference 01
Aggarwal, P., et al. Cancer Cell 18 (4) :329-340 (2010)
Background Reference 02
Abbas, T., et al. Mol. Cell 40 (1) :9-21 (2010)
Background Reference 03
Lv, X.B., et al. J. Biol. Chem. 285 (24) :18234-18240 (2010)
Background Reference 04
Kerzendorfer, C., et al. Hum. Mol. Genet. 19 (7) :1324-1334 (2010)
Other Product Names
Cullin-4A, CUL-4A, CUL4A
Tested Applications
WB
Protein ID
108936013
Physical Properties
Liquid
Curated Selection
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