CAPN11 Antibody
Product Specifications
Background
Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis.
NCBI Gene ID
11131
Swiss Prot
Q9UMQ6
Accession Number
Q9UMQ6
Host
Rabbit
Reactivity
Human
Immunogen
This CAPN11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the Central region of human CAPN11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Symbol
CAPN11
NCBI Official Name
Calpain-11
NCBI Organism
Homo sapiens
Background Reference 01
Ben-Aharon, I., et al. Mol. Reprod. Dev. 73 (6) :767-773 (2006)
Background Reference 02
Dear, T.N., et al. Genomics 59 (2) :243-247 (1999)
Background Reference 03
Rojas, F.J., et al. Mol. Hum. Reprod. 5 (6) :520-526 (1999)
Background Reference 04
Saido, T.C., et al. FASEB J. 8 (11) :814-822 (1994)
Other Product Names
Calpain-11, 3422-, Calcium-activated neutral proteinase 11, CANP 11, CAPN11
Tested Applications
WB, IHC-P
Protein ID
218511961
Physical Properties
Liquid
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