EDN2 Antibody
Product Specifications
Background
This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. [provided by RefSeq].
NCBI Gene ID
1907
Swiss Prot
P20800
Accession Number
P20800
Host
Rabbit
Reactivity
Human
Immunogen
This EDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the C-terminal region of human EDN2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
EDN2
NCBI Official Name
Endothelin-2
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Darrah, R., et al. Physiol. Genomics 41 (1) :71-77 (2010)
Background Reference 03
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 04
Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :
Other Product Names
Endothelin-2, ET-2, Preproendothelin-2, PPET2, EDN2
Tested Applications
WB
Protein ID
119615
Physical Properties
Liquid
Frequently Asked Questions
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