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CEACAM3 Antibody

Product Specifications

Background

This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

NCBI Gene ID

1084

Swiss Prot

P40198

Accession Number

P40198

Host

Rabbit

Reactivity

Human

Immunogen

This CEACAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human CEACAM3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-311

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Symbol

CEACAM3

NCBI Official Name

Carcinoembryonic antigen-related cell adhesion molecule 3

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Tsavaris, N., et al.Chemother 21 (6) :673-680 (2009)

Background Reference 03

Skubitz, K.M., et al.Transl Med 6, 78 (2008) :

Background Reference 04

Stern-Ginossar, N., et al. J. Immunol. 179 (7) :4424-4434 (2007)

Other Product Names

Carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen CGM1, CD66d, CEACAM3, CD66D, CGM1

Tested Applications

WB, IHC-P

Protein ID

218511974

Physical Properties

Liquid

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