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CCR9 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.

NCBI Gene ID

10803

Swiss Prot

P51686

Accession Number

P51686

Host

Rabbit

Reactivity

Human

Immunogen

This CCR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 amino acids from the C-terminal region of human CCR9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CCR9

NCBI Official Name

C-C chemokine receptor type 9

NCBI Organism

Homo sapiens

Background Reference 01

Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

Background Reference 02

Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

Background Reference 03

Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)

Background Reference 04

Segat, L., et al. Vaccine 28 (10) :2201-2206 (2010)

Other Product Names

C-C chemokine receptor type 9, C-C CKR-9, CC-CKR-9, CCR-9, G-protein coupled receptor 28, GPR-9-6, CDw199, CCR9, GPR28

Tested Applications

WB

Protein ID

114152781

Physical Properties

Liquid

Curated Selection

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