MGAT5 Antibody

Product Specifications

Background

This gene encodes mannosyl (alpha-1,6-) -glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, a glycosyltransferase involved in the synthesis of protein-bound and lipid-bound oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the encoded protein's activity may correlate with the progression of invasive malignancies.

NCBI Gene ID

4249

Swiss Prot

Q09328

Accession Number

Q09328

Host

Rabbit

Reactivity

Human

Immunogen

This MGAT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 652-680 amino acids from the C-terminal region of human MGAT5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

85 kDa

Fragment

Rabbit Ig

Symbol

MGAT5

NCBI Official Name

Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

NCBI Organism

Homo sapiens

Background Reference 01

Dick, D.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (6), 1179-1188 (2010) :

Background Reference 02

Brynedal, B., et al. J. Neuroimmunol. 220 (1-2), 120-124 (2010) :

Background Reference 03

Benson, V., et al. Int. Immunol. 22 (3) :167-177 (2010)

Background Reference 04

Wang, C., et al. J. Cell. Biochem. 109 (1) :113-123 (2010)

Other Product Names

Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase, GlcNAc-T V, GNT-V, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V, MGAT5, GGNT5