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SCGB1D2 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.

NCBI Gene ID

10647

Swiss Prot

O95969

Accession Number

O95969

Host

Rabbit

Reactivity

Human

Immunogen

This SCGB1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the Central region of human SCGB1D2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

10 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SCGB1D2

NCBI Official Name

Secretoglobin family 1D member 2

NCBI Organism

Homo sapiens

Background Reference 01

Sjodin, A., et al. Anticancer Res. 28 (3A), 1493-1498 (2008) :

Background Reference 02

Culleton, J., et al. Int. J. Cancer 120 (5) :1087-1092 (2007)

Background Reference 03

Sjodin, A., et al. Acta Neuropathol. 109 (4) :381-386 (2005)

Background Reference 04

Carter, D., et al. Clin. Cancer Res. 9 (2) :749-754 (2003)

Other Product Names

Secretoglobin family 1D member 2, Lipophilin-B, SCGB1D2, LIPHB, LPNB

Tested Applications

WB

Physical Properties

Liquid

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