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PIK3IP1 Antibody

Product Specifications

Background

PIK3IP1 is a novel protein that shares homology with the p85 subunit of phosphatidylinositol-3-Kinases (PI3Ks) . The PI3K is essential for cell proliferation and Survival. The PIK3IP down regulates the activity of the PI3K and induces apoptosis by associating with p85 and p110 to form a complex, using the p85-like domain. However, there is no evidence to suggest that the PIK3IP1 prevents association of p85 and p110 as they associate with very high affinity.

NCBI Gene ID

113791

Swiss Prot

Q96FE7

Accession Number

Q96FE7

Host

Rabbit

Reactivity

Human

Immunogen

This PIK3IP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the C-terminal region of human PIK3IP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PIK3IP1

NCBI Official Name

Phosphoinositide-3-kinase-interacting protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Gao, P., et al. Beijing Da Xue Xue Bao 40 (6) :572-577 (2008)

Background Reference 02

He, X., et al. Cancer Res. 68 (14) :5591-5598 (2008)

Background Reference 03

Zhu, Z., et al. Biochem. Biophys. Res. Commun. 358 (1) :66-72 (2007)

Background Reference 04

Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)

Other Product Names

Phosphoinositide-3-kinase-interacting protein 1, Kringle domain-containing protein HGFL, PIK3IP1, HGFL

Tested Applications

WB

Protein ID

134034149

Physical Properties

Liquid

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