LAIR1 Antibody
Product Specifications
Background
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
NCBI Gene ID
3903
Swiss Prot
Q6GTX8
Accession Number
Q6GTX8
Host
Rabbit
Reactivity
Human
Immunogen
This LAIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human LAIR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LAIR1
NCBI Official Name
Leukocyte-associated immunoglobulin-like receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 02
Brondijk, T.H., et al. Blood 115 (7) :1364-1373 (2010)
Background Reference 03
Tang, X., et al. J. Immunol. 182 (9) :5446-5452 (2009)
Background Reference 04
Lebbink, R.J., et al. Matrix Biol. 28 (4) :202-210 (2009)
Other Product Names
Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305, LAIR1, CD305
Tested Applications
WB
Protein ID
74736490
Physical Properties
Liquid
Frequently Asked Questions
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