NONO Antibody

Product Specifications

Background

This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq].

NCBI Gene ID

4841

Swiss Prot

Q15233

Accession Number

Q15233

Host

Rabbit

Reactivity

Human

Immunogen

This NONO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human NONO.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

NONO

NCBI Official Name

Non-POU domain-containing octamer-binding protein

NCBI Organism

Homo sapiens

Background Reference 01

Marko, M., et al. Exp. Cell Res. 316 (3) :390-400 (2010)

Background Reference 02

Dong, X., et al. Mol. Endocrinol. 23 (8) :1147-1160 (2009)

Background Reference 03

Sikora, D., et al. Virology 390 (1) :71-78 (2009)

Background Reference 04

Clemson, C.M., et al. Mol. Cell 33 (6) :717-726 (2009)

Other Product Names

Non-POU domain-containing octamer-binding protein, NonO protein, 54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, DNA-binding p52/p100 complex, 52 kDa subunit, NMT55, p54 (nrb), p54nrb, NONO, NRB54