NR0B1 Antibody

Product Specifications

Background

This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

NCBI Gene ID

190

Swiss Prot

P51843

Accession Number

P51843

Host

Rabbit

Reactivity

Human

Immunogen

This NR0B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human NR0B1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Symbol

NR0B1

NCBI Official Name

Nuclear receptor subfamily 0 group B member 1

NCBI Organism

Homo sapiens

Background Reference 01

Li, N., et al. J. Clin. Endocrinol. Metab. 95 (9), E104-E111 (2010) :

Background Reference 02

Nedumaran, B., et al. J. Biol. Chem. 285 (12) :9221-9232 (2010)

Background Reference 03

Kinsey, M., et al. Cancer Res. 69 (23) :9047-9055 (2009)

Background Reference 04

Nagl, F., et al. Am. J. Physiol., Cell Physiol. 297 (5), C1146-C1156 (2009) :

Other Product Names

Nuclear receptor subfamily 0 group B member 1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, NR0B1, AHC, DAX1

Tested Applications

WB, IHC-P

Protein ID

20532385

Physical Properties

Liquid

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