SYT2 Antibody

Product Specifications

Background

Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]) .

NCBI Gene ID

127833

Swiss Prot

Q8N9I0

Accession Number

Q8N9I0

Host

Rabbit

Reactivity

Human

Immunogen

This SYT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 amino acids from the Central region of human SYT2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SYT2

NCBI Official Name

Synaptotagmin-2

NCBI Organism

Homo sapiens

Background Reference 01

Young, S.M. Jr., et al. Neuron 63 (4) :482-496 (2009)

Background Reference 02

Han, C., et al. J. Immunol. 182 (5) :2986-2996 (2009)

Background Reference 03

Laohavisit, A., et al. Plant Cell 21 (2) :479-493 (2009)

Background Reference 04

Shi, J., et al. Biochem. Biophys. Res. Commun. 374 (2) :331-335 (2008)

Other Product Names

Synaptotagmin-2, Synaptotagmin II, SytII, SYT2

Tested Applications

Protein ID

116242811

Physical Properties

Liquid

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