PPP3CA Antibody

Product Specifications

Background

Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.

NCBI Gene ID

5530

Swiss Prot

Q08209

Accession Number

Q08209

Host

Rabbit

Reactivity

Human

Immunogen

This PPP3CA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-466 amino acids from the C-terminal region of human PPP3CA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPP3CA

NCBI Official Name

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

NCBI Organism

Homo sapiens

Background Reference 01

He, Z.H., et al. Eur. J. Appl. Physiol. 110 (4) :761-767 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Chiocco, M.J., et al. Subst Use Misuse 45 (11) :1809-1826 (2010)

Background Reference 04

Yang, D., et al. Int. J. Mol. Med. 26 (1) :159-164 (2010)

Other Product Names

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform, PPP3CA, CALNA, CNA