MSN Antibody

Product Specifications

Background

Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.

NCBI Gene ID

4478

Swiss Prot

P26038

Accession Number

P26038

Host

Rabbit

Reactivity

Human

Immunogen

This MSN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-487 amino acids from the C-terminal region of human MSN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

68 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MSN

NCBI Official Name

Moesin

NCBI Organism

Homo sapiens

Background Reference 01

Gloerich, M., et al. Mol. Cell. Biol. 30 (22) :5421-5431 (2010)

Background Reference 02

Lee, J.H., et al. Yonsei Med. J. 51 (3) :438-447 (2010)

Background Reference 03

Takahashi, E., et al. J. Biol. Chem. 285 (6) :4060-4073 (2010)

Background Reference 04

He, M., et al. BMC Cancer 10, 170 (2010) :

Other Product Names

Moesin, Membrane-organizing extension spike protein, MSN

Tested Applications

Protein ID

127234

Physical Properties

Liquid

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