HIST1H1D Antibody
Product Specifications
Background
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
NCBI Gene ID
3007
Swiss Prot
P16402
Accession Number
P16402
Host
Rabbit
Reactivity
Human
Immunogen
This HIST1H1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human HIST1H1D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Symbol
HIST1H1D
NCBI Official Name
Histone H1.3
NCBI Organism
Homo sapiens
Background Reference 01
Kim, J.J., et al. J. Hum. Genet. 55 (1) :27-31 (2010)
Background Reference 02
Soranzo, N., et al. PLoS Genet. (4), E1000445 (2009) :
Background Reference 03
Sovio, U., et al. PLoS Genet. (3), E1000409 (2009) :
Background Reference 04
Gudbjartsson, D.F., et al. Nat. Genet. 40 (5) :609-615 (2008)
Other Product Names
Histone H13, Histone H1c, Histone H1s-2, HIST1H1D, H1F3
Tested Applications
WB, IHC-P
Protein ID
121925
Physical Properties
Liquid
Curated Selection
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