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NCK1 Antibody

Product Specifications

Background

The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.

NCBI Gene ID

4690

Swiss Prot

P16333

Accession Number

P16333

Host

Rabbit

Reactivity

Human

Immunogen

This NCK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human NCK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-226

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Symbol

NCK1

NCBI Official Name

Cytoplasmic protein NCK1

NCBI Organism

Homo sapiens

Background Reference 01

Barda-Saad, M., et al. EMBO J. 29 (14) :2315-2328 (2010)

Background Reference 02

Gehmlich, K., et al. Eur. J. Cell Biol. 89 (5) :351-364 (2010)

Background Reference 03

Preisinger, C., et al. Cell. Signal. 22 (5) :848-856 (2010)

Background Reference 04

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Other Product Names

Cytoplasmic protein NCK1, NCK adaptor protein 1, Nck-1, SH2/SH3 adaptor protein NCK-alpha, NCK1, NCK

Tested Applications

WB, IHC-P

Protein ID

127962

Physical Properties

Liquid

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