NCK1 Antibody
Product Specifications
Background
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
NCBI Gene ID
4690
Swiss Prot
P16333
Accession Number
P16333
Host
Rabbit
Reactivity
Human
Immunogen
This NCK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human NCK1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
NCK1
NCBI Official Name
Cytoplasmic protein NCK1
NCBI Organism
Homo sapiens
Background Reference 01
Barda-Saad, M., et al. EMBO J. 29 (14) :2315-2328 (2010)
Background Reference 02
Gehmlich, K., et al. Eur. J. Cell Biol. 89 (5) :351-364 (2010)
Background Reference 03
Preisinger, C., et al. Cell. Signal. 22 (5) :848-856 (2010)
Background Reference 04
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Other Product Names
Cytoplasmic protein NCK1, NCK adaptor protein 1, Nck-1, SH2/SH3 adaptor protein NCK-alpha, NCK1, NCK
Tested Applications
WB, IHC-P
Protein ID
127962
Physical Properties
Liquid
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