FCGR2A Antibody

Product Specifications

Background

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

2212

Swiss Prot

P12318

Accession Number

P12318

Host

Rabbit

Reactivity

Human

Immunogen

This FCGR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the C-terminal region of human FCGR2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FCGR2A

NCBI Official Name

Low affinity immunoglobulin gamma Fc region receptor II-a

NCBI Organism

Homo sapiens

Background Reference 01

Dornan, D., et al. Blood 116 (20) :4212-4222 (2010)

Background Reference 02

Zhang, C.Y., et al. J. Biol. Chem. 285 (44) :34250-34258 (2010)

Background Reference 03

Iwasaki, M., et al. Breast Cancer Res. Treat. (2010) In press :

Background Reference 04

Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :

Other Product Names

Low affinity immunoglobulin gamma Fc region receptor II-a, IgG Fc receptor II-a, CDw32, Fc-gamma RII-a, Fc-gamma-RIIa, FcRII-a, CD32, FCGR2A, CD32, FCG2, FCGR2A1, IGFR2