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STAT4 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.

NCBI Gene ID

6775

Swiss Prot

Q14765

Accession Number

Q14765

Host

Rabbit

Reactivity

Human

Immunogen

This STAT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-695 amino acids from the C-terminal region of human STAT4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-222

Calculated Molecular Weight

86 kDa

Fragment

Rabbit Ig

Symbol

STAT4

NCBI Official Name

Signal transducer and activator of transcription 4

NCBI Organism

Homo sapiens

Background Reference 01

Plant, D., et al. Ann. Rheum. Dis. 69 (8) :1548-1553 (2010)

Background Reference 02

Gestermann, N., et al. Genes Immun. 11 (5) :432-438 (2010)

Background Reference 03

Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)

Background Reference 04

Vuong, M.T., et al. PLoS ONE (5), E10559 (2010) :

Other Product Names

Signal transducer and activator of transcription 4, STAT4

Tested Applications

WB, IHC-P, IF

Protein ID

6226158

Physical Properties

Liquid

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